%0 Journal Article %T Electrochemical Approach for Determination of Tertahydrozoline HCl Using Gold nanoparticles Electrode %J Analytical and Bioanalytical Electrochemistry %I Analytical and Bioanalytical Electrochemistry is an international scientific journal, which is published online every 3 months (since 2009), every 2 months (since 2011) and monthly (since 2018) by Center of Excellence in Electrochemistry, University of Tehran %Z - %A A. Habib, Ahmed %A A. M. Hendawy, Hassan %A F. Hammad, Sherin %A I. Bebawy, Lories %A A. Girges, Marian %D 2020 %\ 02/01/2020 %V 12 %N 2 %P 223-237 %! Electrochemical Approach for Determination of Tertahydrozoline HCl Using Gold nanoparticles Electrode %K Tetrahydrozoline %K Voltammetry %K Gold nanoparticles %K Carbon paste %K surfactant %K Electroanalysis %R %X The electrochemical behavior of tetrahydrozoline (THZ) was explored by cyclic voltammetry and differential pulse voltammetry. A well-defined peak at 915 mV using gold nanomodified electrode (AuNPts/CP) in presence of sodium dodecyl sulphate (SDS) was detected. Different buffers, pH and scan rates on oxidation peak current were studied. Linear calibration curve was achieved in the range of 1.99×10−5 to 7.79×10-5 M with a limit of detection (LOD) 5.54×10-6 M and limit of quantification (LOQ) 1.69×10−5 M, respectively.The suggested method was successfully utilized to the eye drops dosage form and urine sample with percentage recovery, 98.86%±0.77, and 101.13±0.62, respectively. %U https://www.abechem.com/article_38716_494dde559669286767453136e2cf97b7.pdf