**Authors**

Center of Excellence in Electrochemistry, School of Chemistry, University of Tehran, Tehran, Iran

**Abstract**

A new selectophore was introduced for Cu^{2+} ions. Spectroscopic studies showed a selectivity of a new organic compound (L) toward copper ions and several transitional metal ions. Hence, L was utilized in designing several ion selective electrodes for these cations. In practice, Cu^{2+} ion selective electrode behaved Nernstian (slope of 27.95±0.3 mV decade^{-1}) over a wide linear range of 1.0×10^{-6}-1.0×10^{-2} mol L^{-1}. Optimum performance of the indicator electrode was observed by a membrane containing 7% selectophore, 2% sodium tetraphenyl borate (NaTPB) as an ionic additive, 61% nitrobenzene (NB) as solvent mediator and 30% polyvinyl chloride (PVC). The sensor showed a short response time of about 20 s and an acceptable life time, the potentiometric response is independent on the pH of the solution in the range of 3.5-7. The optimized copper sensor was used for analysis of copper content of some blood plasma samples. The obtained results were in good agreements with ICP-OES method.

**Keywords**

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