@article { author = {A. Habib, Ahmed and A. M. Hendawy, Hassan and F. Hammad, Sherin and I. Bebawy, Lories and A. Girges, Marian}, title = {Electrochemical Approach for Determination of Tertahydrozoline HCl Using Gold nanoparticles Electrode}, journal = {Analytical and Bioanalytical Electrochemistry}, volume = {12}, number = {2}, pages = {223-237}, year = {2020}, publisher = {Analytical and Bioanalytical Electrochemistry is an international scientific journal, which is published online every 3 months (since 2009), every 2 months (since 2011) and monthly (since 2018) by Center of Excellence in Electrochemistry, University of Tehran}, issn = {-}, eissn = {2008-4226}, doi = {}, abstract = {The electrochemical behavior of tetrahydrozoline (THZ) was explored by cyclic voltammetry and differential pulse voltammetry. A well-defined peak at 915 mV using gold nanomodified electrode (AuNPts/CP) in presence of sodium dodecyl sulphate (SDS) was detected. Different buffers, pH and scan rates on oxidation peak current were studied. Linear calibration curve was achieved in the range of 1.99×10−5 to 7.79×10-5 M with a limit of detection (LOD) 5.54×10-6 M and limit of quantification (LOQ) 1.69×10−5 M, respectively.The suggested method was successfully utilized to the eye drops dosage form and urine sample with percentage recovery, 98.86%±0.77, and 101.13±0.62, respectively.}, keywords = {Tetrahydrozoline,Voltammetry,Gold nanoparticles,Carbon paste,surfactant,Electroanalysis}, url = {https://www.abechem.com/article_38716.html}, eprint = {https://www.abechem.com/article_38716_494dde559669286767453136e2cf97b7.pdf} }