%0 Journal Article %T Determination of Copper Content of Human Blood Plasma by an Ion Selective Electrode based on a New Copper-Selectophore %J Analytical and Bioanalytical Electrochemistry %I Analytical and Bioanalytical Electrochemistry is an international scientific journal, which is published online every 3 months (since 2009), every 2 months (since 2011) and monthly (since 2018) by Center of Excellence in Electrochemistry, University of Tehran %Z - %A Faridbod, Farnoush %A Bahman, Mina %D 2020 %\ 06/01/2020 %V 12 %N 6 %P 881-892 %! Determination of Copper Content of Human Blood Plasma by an Ion Selective Electrode based on a New Copper-Selectophore %K copper %K Selectophore %K sensor %K Potentiometry %K Ion selective electrode %R %X A new selectophore was introduced for Cu2+ ions. Spectroscopic studies showed a selectivity of a new organic compound (L) toward copper ions and several transitional metal ions. Hence, L was utilized in designing several ion selective electrodes for these cations. In practice, Cu2+ ion selective electrode behaved Nernstian (slope of 27.95±0.3 mV decade-1) over a wide linear range of 1.0×10-6-1.0×10-2 mol L-1. Optimum performance of the indicator electrode was observed by a membrane containing 7% selectophore, 2% sodium tetraphenyl borate (NaTPB) as an ionic additive, 61% nitrobenzene (NB) as solvent mediator and 30% polyvinyl chloride (PVC). The sensor showed a short response time of about 20 s and an acceptable life time, the potentiometric response is independent on the pH of the solution in the range of 3.5-7. The optimized copper sensor was used for analysis of copper content of some blood plasma samples. The obtained results were in good agreements with ICP-OES method. %U https://www.abechem.com/article_43211_e049542f179031c8e94b9998e5a43f14.pdf