Analytical and Bioanalytical Electrochemistry is an international scientific journal published online by the Center of Excellence in Electrochemistry at the University of Tehran, Tehran, Iran. The journal was published quarterly from 2009 to 2011, bimonthly from 2011 to 2018, and has been published in at least eight issues per year since 2018. Analytical and Bioanalytical Electrochemistry - 16 6 2024 06 30 Electrochemical Investigation of The Inhibitory Effect of Zinc Oxide Nanoparticles/Tenofovir Disoproxil Fumarate Nanocomposite on Mild Steel Corrosion in 1 M Hydrochloric Acid 559 567 714079 10.22034/abec.2024.714079 EN Msenhemba Moses Mchihi Department of Chemical Science, School of Science, Yaba College of Technology Lagos, Nigeria Nnenna Winifred Odozi Department of Chemistry, Faculty of Science, University of Ibadan, Nigeria Shittu Alhameen Gbolahan Department of Science Education, School of Technical Education, Yaba College of Technology Lagos, Nigeria Journal Article 2024 01 12 Corrosion of mild steel is a disturbing phenomenon that deserves effective measures to avert accidents, equipment breakdown, and economic downturns. The corrosion inhibitory potentials of zinc oxide nanoparticles/tenofovir disoproxil fumarate nanocomposite (Z+D) was investigated using potentiodynamic polarization (PDP) and electrochemical impedance spectroscopy (EIS).  PDP analysis revealed that the alteration in corrosion potential values in the presence of Z+D (compared to corrosion potential obtained in the absence of Z+D) was less than 85 mV which suggest that Z+D operated as a mixed-type inhibitor. Corrosion current density (I_corr) decreased tremendously from 1241 μAcm^-2 (in the absence of Z+D) to 321 μA<br />cm^-2 in the presence of 1000 ppm of the inhibitor. The inhibition efficiency increased with an increase in concentration of inhibitor to reach 74% when 1000 ppm of the inhibitor was introduced. EIS studies revealed a tremendous increase in charge transfer resistance (R_ct) from 3533 Ω cm² (in the absence of the inhibitor) to 21464×cm² when 1000 ppm of Z+D was introduced. The highest inhibition efficiency (i.e 84%) computed from EIS analysis was obtained when 1000 ppm of the inhibitor was introduced. Electrochemical findings suggest that Z+D exhibited good attributes as a corrosion inhibitor for mild steel in 1 M hydrochloric acid. https://www.abechem.com/article_714079_404dfc7703ffb7d9fdae67e328f960c7.pdf