Analytical and Bioanalytical Electrochemistry is an international scientific journal published online by the Center of Excellence in Electrochemistry at the University of Tehran, Tehran, Iran. The journal was published quarterly from 2009 to 2011, bimonthly from 2011 to 2018, and has been published in at least eight issues per year since 2018. Analytical and Bioanalytical Electrochemistry - 16 8 2024 08 31 Synthesis and Characterization of Tetraaza-Macrocyclic Complexes of MnII and NiII: Electrochemical and Antibacterial Evaluation 728 736 715423 10.22034/abec.2024.715423 EN Vinod Kumar Vashistha Department of Chemistry, University of Lucknow, Lucknow-226007, India Dipak Kumar Das Department of Chemistry, GLA University, Mathura-281406, India 0000-0002-1718-0218 Bhaskar Vallamkonda Department of Pharmaceutical Science, VIGNAN'S Foundation for Science, Technology & Research, Vadlamudi, Guntur-522213, Andhra Pradesh, India Suman Yadav Department of Chemistry, Swami Shraddhanand College, University of Delhi, Delhi-110036, India Journal Article 2024 03 28 Macrocyclic complexes play a crucial role in various emerging fields, including electrocatalysis, catalysis, sensor technology, pharmaceuticals, and biological applications. In this study, we synthesized a tetraaza-macrocyclic cavity capable of hosting transition metals, specifically Mn^II and Ni^II, forming the MnN₄ and NiN₄-macrocyclic complexes, respectively. Structural analyses were performed to propose the configuration of these complexes. Additionally, electrochemical studies were conducted to assess their redox potential and electron transfer kinetics. Furthermore, the biological activity of the complexes as antibacterial agents against a broad spectrum of microorganisms was investigated. The findings revealed that these complexes exhibit favorable redox properties with rapid electron transfer kinetics. The cyclic voltammogram was showed interesting results by eliminating ligand oxidation redox couple were observed as comparable in DMSO with shifting of 0.13 V peak potential in -ve peak potential range with the decreament in peak height. These results underscore the multifaceted applications of tetraaza-macrocyclic complexes in diverse fields, highlighting their importance in both fundamental research and practical biomedical interventions. https://www.abechem.com/article_715423_eb3f82a07b007bb7f9fd54dd96bc04ec.pdf