Analytical and Bioanalytical Electrochemistry is an international scientific journal, which is published online every 3 months (since 2009), every 2 months (since 2011) and monthly (since 2018) by Center of Excellence in Electrochemistry, University of Tehran Analytical and Bioanalytical Electrochemistry - 12 1 2020 01 31 Modeling and Optimization of the Electrochemical Process for Cefixime Removal from Water 36 47 717559 EN Roqiyeh Mostafaloo Student Research Committee, Qom university of medical sciences, Qom, Iran 0000-0002-5415-0755 Mahdi Asadi-Ghalhari Research Center for Environmental Pollutants, Qom University of Medical Sciences, Qom, Iran 0000-0003-3718-3261 Journal Article 2019 10 07 Pharmaceutical compounds such as Cefixime (CFX) as an antibiotic were detected in water resources. These compounds in water has caused many problems including bacterial resistance to antibiotics. Some processes have been used to remove these compounds from water sources. In this research the effect of electrocoagulation process was investigated on CFX removal from water. Experiments were carried out as a batch mode in electrochemical reactor that was made from Plexiglas with dimensions of 10×15×10 cm (1 L volume) and Aluminum/Aluminum electrodes (48 cm2 effective area) that immersed vertically, monopole configuration and in parallel. Central Composite Design (CCD) utilizing a response surface methodology (RSM) was used with experimental points of pH, Initial CFX concentration, current intensity and Reaction time and employed by different model such as linear, interaction and quadratic models. The results of this study showed that the efficiency of four dependent parameters on CFX removal represent with four linear and six interactions effects that the reaction time and initial concentration of CFX have the most positive and negative effects on the removal of CFX (%), respectively. The optimum conditions for the electrocoagulation process was pH=7.5, a primary concentration of CFX=5.75 mg/L, a current intensity=6.0 amperes and a reaction time=72.5 minutes (CFX removal=85.6%). https://www.abechem.com/article_717559_965a27ccb270bdab051a56c1dbd96e42.pdf