Yogendra Kumar; Vinod Kumar Vashistha; Vivek Sharma; Rahul Patil; Dipak Kumar Das
Volume 12, Issue 5 , May 2020, , Pages 653-662
Abstract
Manganese ferrite nanoparticles were produced by applying the combustion technique using the manganese acetate and ferric nitrate as the starting material. Analytical techniques like FESEM and TEM were utilized to characterize the synthesized materials. The typical size was observed in the range of 12 ...
Read More
Manganese ferrite nanoparticles were produced by applying the combustion technique using the manganese acetate and ferric nitrate as the starting material. Analytical techniques like FESEM and TEM were utilized to characterize the synthesized materials. The typical size was observed in the range of 12 to 14 nm with a cubic structure. The synthesized material was used as an electrochemical sensor which was fabricated using the nanocomposite for the identification of guanine (GU) and uric acid (UA) (individually and in their mixture). The cyclic voltammeter and differential pulse voltammeter techniques were deployed to check the sensor activity of the modified electrode. Lower detection limit for GU and UA was found to be 400 nM and 450 nM, with linearity range 0.5 to 120 μM and 02 to 140 μM for GU and UA respectively. The electrochemical sensor developed in this method can be widely employed for the identification of GU and UA and analogs in biofluids or dosage forms.
Ali Babaei; Akbar Yousefi
Volume 12, Issue 4 , April 2020, , Pages 486-501
Abstract
In this study a novel method was developed to fabricate cadmium sulfide nanoparticles/multiwalled carbon nanotubes composite modified gold electrode (CdSNPs/MWCNTS/AuE) to measure trace amounts of norepinephrine(NE), indomethacin (IND), and uric acid (UA) simultaneously. Electrochemical investigations ...
Read More
In this study a novel method was developed to fabricate cadmium sulfide nanoparticles/multiwalled carbon nanotubes composite modified gold electrode (CdSNPs/MWCNTS/AuE) to measure trace amounts of norepinephrine(NE), indomethacin (IND), and uric acid (UA) simultaneously. Electrochemical investigations were carried out using cyclic voltammetry (CV), differential pulse voltammetry (DPV) and chronoamprometery (CA) methods. Using DPV method under optimum condition, the NE anodic peak current represented a linear relationship in the two concentration ranges of 0.3 to 100.0 μM and 100.0 to 500.0 μM. For UA, the corresponding anodic peak current showed linear ranges from 0.5 to 100.0 μM and from 100.0 to 350.0 μM, and IND the corresponding linear range was between 2.0 to 80.0 μM, respectively. Detection limits have been calculated equal to 0.16 μM for NE, 0.09 μM for UA, and 0.46 μM for IND, respectively. The modified electrode has been applied for the determination of NE, UA and IND in human urine and blood serum with satisfactory results.
Mohammad Mazloum-Ardakani; Ali Mohammad Dehghani-Tafti
Volume 12, Issue 2 , February 2020, , Pages 277-288
Abstract
The electrochemical properties of a modified carbon paste electrode with the synthesized compound of 2,2'-[1,7–heptanediylbis(nitrilomethylidene)]-bis(4-hydroxyphenol) (DHBH) and graphite nanoparticle (GN) were studied by cyclic voltammetry (CV), chronoamperometry and differential pulse voltammetry ...
Read More
The electrochemical properties of a modified carbon paste electrode with the synthesized compound of 2,2'-[1,7–heptanediylbis(nitrilomethylidene)]-bis(4-hydroxyphenol) (DHBH) and graphite nanoparticle (GN) were studied by cyclic voltammetry (CV), chronoamperometry and differential pulse voltammetry (DPV) methods. The proposed electrode shows excellent electrocatalytic activity towards the oxidation of NADH under the optimum pH of 7.0. The modifier and nanoparticle simultaneously lead to a reduce overpotential of NADH oxidation about 250 mV and enhance current about 6 μA of the unmodified CPE. This electrochemical sensor exhibited a detection limit (3σ) of 13.4 nM with two linear dynamic ranges (0.01-6.0 and 6.0-400.0 μM) for the determination of NADH. The modified electrode can detect well NADH (180 mV) in the presence of Uric acid (360 mV) simultaneously. Also, the performance of the proposed sensor was evaluated in real samples.
