Document Type : Review
Center of Excellence in Electrochemistry, School of Chemistry, College of Science, University of Tehran, Tehran, Iran
Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Science Institute, Tehran University of Medical Sciences, Tehran, Iran
Biosensor Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
Tamoxifen (TAM) is a selective estrogen receptor modulator used in the treatment of breast cancer, women’s infertility and some other endocrine diseases. TAM is a generic medication that is prescribed relatively a lot. Due to the impact of this medication and its side effects, screening TAM level in biological samples and in pharmaceutical formulations are of great importance. Various analytical techniques are developed for the detection or monitoring TAM levels in different matrices. Since TAM chemical structure is able to undergo electrochemical oxidation, electrochemical techniques due to their remarkable features are also considered as analytical methods. Here, electroanalytical measurements of TAM will be reviewed.