FFTSW Voltammetric Sensor based on Eu2(CO3)3 Nanoparticles for Sulfadiazine Determination

Document Type : Original Article


Center of Excellence in Electrochemistry, School of Chemistry, College of Science, University of Tehran, Tehran, Iran


In this work, a new sensitive sensor based on application of fast Fourier transform square wave voltammetry (FFTSWV) for determination of sulfadiazine is described. The developed sensor is a modified carbon paste electrode with Eu2(CO3)3 nanoparticles. The characterization of the used materials was done through transmission electron microscopy (TEM) and FT-IR   spectroscopy. The cyclic voltammogram of sulfadiazine showed a well-resolved irreversible oxidation peak at around 0.85 V vs. Ag/AgCl.  After optimization of experimental conditions, such as pH, percentage of modifier, amplitude, number of cycle and frequency a linear calibration curve was obtained in the concentration ranges of 1.0×10-6 – 250.0×10-6 M with a limit of detection 0.4×10-7 M. The proposed sensor was successfully applied for the determination of sulfadiazine in pharmaceutical sample with the RSD range of 0.7 to 1.7.