Electrochemical Sensor Facilitated by the Synthesis of Cadmium Oxide Nanoparticles Amplified Pre-treated Carbon Paste Electrode for Quantification of Serotonin in the Presence of Epinephrine

Document Type : Original Article


Department of P.G. Studies and Research in Industrial Chemistry, JnanaSahyadri, Kuvempu University, Shankaraghatta-577 451, Shivamogga, Karnataka, India


Herein, the modest co-precipitation mode was implemented to fabricate the cadmium oxide nanoparticles (CdO/NPs). The size, elemental composition and morphological characteristics of the synthesized nanomaterials were confirmed by XRD, EDX and SEM measurements. The designed CdO nanoparticles were exploited for the amplification followed by pre-treatment of carbon paste electrode (CdO/MPCPE) and successfully utilised for the quantification of serotonin (SE) in the presence of epinephrine (EP) at biological pH.  The tailored composite sensor proclaims the rapid electron transport behaviour which results in accretion in the oxidation peak signals for SE and EP. The several experimental conditions includes pH of supportive buffer, speed rate and concentration of analytes species were idealised. The CdO/MPCPE displays better sensing capability towards specific and simultaneous quantifications and lower detection limits were achieved. The customised electrode facilitates the high selectivity, excellent electrocatalytic stability, and agreeable results for rapid diagnosis of identical bioactive entities.


Volume 15, Issue 2
February 2023
Pages 102-117
  • Receive Date: 23 December 2022
  • Revise Date: 22 February 2023
  • Accept Date: 23 February 2023
  • First Publish Date: 28 February 2023