Simultaneous Determination of Acetaminophen in the Presence of Adrenaline at BiVO4/MCPE: A Cyclic Voltammetry Study

K G, Manjunath; Swamy, B E Kumara; Murthy, K. A. Vishnu; Kumar, Mohan

doi:10.22034/abec.2023.705133

Simultaneous Determination of Acetaminophen in the Presence of Adrenaline at BiVO4/MCPE: A Cyclic Voltammetry Study

Document Type : Original Article

Authors

Manjunath K G ¹

B E Kumara Swamy ²

K. A. Vishnu Murthy ¹

Mohan Kumar ³

¹ Dept of Industrial Chemistry, Sir M.V. Science College, Bhadravathi, Karnataka(S), India

² Dept of PG Studies and Research in Industrial Chemistry, Kuvempu University, Jnana Sahyadri, Shankaraghatta (577451) Shivamogga (D) Karnataka(S), India

³ Dept of Chemistry, PES Institute of Technology and Management, Sagar Road, Guddada Irakere, Kotegangoor-577204, Shimoga, India

10.22034/abec.2023.705133

Abstract

In the present work, the BiVO₄ nanoparticles (BiVO₄/NPs) were synthesized using the co-precipitation method and characterized by the X-ray diffraction (XRD), scanning electron microscope (SEM) and energy dispersive spectroscopy (EDS) techniques. The BiVO₄/NPs were utilized as electrode modifiers with carbon paste electrode (BiVO₄/MCPE), and the as-prepared modified electrode surface was pretreated with NaOH (BiVO₄/NaOH/MCPE). The pretreated modified electrode was used for the simultaneous determination of acetaminophen (ACOP) and adrenaline (AD) by using cyclic voltammetry (CV) and differential pulse voltammetric (DPV) techniques. The influence of variation of concentration of ACOP and AD was investigated at BiVO₄/NaOH/MCPE. The limit of detection (LOD) and limit of quantification (LOQ) of both ACOP and AD at BiVO₄/NaOH/MCPE, respectively were determined, the LOD was found to be 3.3 µM for ACOP and 5.9 μM for AD, and LOQ was found to be 11.1 µM for ACOP and 17.8 μM for AD, respectively. Moreover, the BiVO₄/NaOH/MCPE is used for the sensitive and selective determination of ACOP and AD in real samples.

Keywords

BiVO4

Nanoparticles

Modified carbon paste electrode

Cyclic voltammetry

Paracetamol

Subjects