Nanocomposite based Electrochemical Sensors for Determination of Some Biologically Important Compounds: A Review

Vashistha, Vinod Kumar; Bala, Renu; Mittal, Ankit; Das, Dipak Kumar; Sharma, Shubham; Pullabhotla, Rajasekhar VSR

doi:10.22034/abec.2023.707326

Nanocomposite based Electrochemical Sensors for Determination of Some Biologically Important Compounds: A Review

Document Type : Review

Authors

Vinod Kumar Vashistha ¹

Renu Bala ²

Ankit Mittal ¹

Dipak Kumar Das ¹

Shubham Sharma ³

Rajasekhar VSR Pullabhotla ⁴

¹ Department of Chemistry, GLA University, Mathura, 281406, India

² Department of Chemistry, Kalindi College, University of Delhi, Delhi, India

³ Department of ASHD, G B Pant Institute of Engineering and Technology, Pauri Garhwal, Uttarakhand, India

⁴ Department of Chemistry, Faculty of Science, Agriculture and Engineering, University of Zululand, P/Bag X1001, KwaDlangezwa, 3886, South Africa

10.22034/abec.2023.707326

Abstract

Electrochemical methods have become increasingly popular in the pharmaceutical and drug analysis sectors due to their numerous benefits, such as high sensitivity, selectivity, and specificity. Electrochemical-based nanomaterials are adjustable and can be influenced by the type of electrode used and the applied potential. Electroanalytical methods have proven to be a useful analytical technology that has seen increased utility in the pharmaceutical business in recent years. In the last five years, there have been significant developments in the synthesis and use of novel electrochemical sensors in drug analysis. These developments have been driven by advancements in instrumentation and an increased understanding of electrochemical methods. This review concludes the current state-of-the-art in electrochemical sensors for pharmaceutical analysis and future perspectives in this field. We highlight the need for more standardized methods for the determination of biologically important compounds such as dopamine, guanine, adenine, and uric acid using electrochemical sensors and the development of multiplexed sensors for simultaneous analysis of multiple drugs.

Keywords

Electrochemical nanosensors

Drug analysis

Cyclic voltammetry

Biochemicals

Nanocomposites

Subjects