A Simple Electrochemical Method to Detect Tetracycline in Honey Samples using Electrochemically Activated Glassy Carbon Electrode in Surfactant Medium

Nguyen, Thu Huong; Le, Diep Quoc Anh; Nguyen, Hoang Phuong Anh; Do, Minh Huy

doi:10.22034/abec.2025.720367

A Simple Electrochemical Method to Detect Tetracycline in Honey Samples using Electrochemically Activated Glassy Carbon Electrode in Surfactant Medium

Document Type : Original Article

Authors

Thu Huong Nguyen ¹^{, 2}

Diep Quoc Anh Le ¹^{, 2}

Hoang Phuong Anh Nguyen ¹^{, 2}

Minh Huy Do ¹^{, 2}

¹ Department of Analytical Chemistry, Faculty of Chemistry, University of Science, Ho Chi Minh City, 227 Nguyen Van Cu, District 5, Ho Chi Minh City, 70000 Vietnam

² Vietnam National University, Ho Chi Minh City, Linh Trung Ward, Thu Duc City, Ho Chi Minh City, 70000 Vietnam

10.22034/abec.2025.720367

Abstract

An electrochemical method for the determination of tetracycline has been reported, employing cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques with an activated glassy carbon electrode serving as the working electrode. In the presence of a suitable surfactant, the peak current enhancement of tetracycline was achieved. The interference effects and their elimination of the electrochemical method were also studied in the presence of various ions. The current responses obtained under the optimum experimental conditions through the DPV technique of tetracycline increased linearly with concentrations in linear dynamic ranges of 1.0 - 10 μmol L^-1and 10 - 100 μmol L^-1 with 0.31 μmol L^-1detection limits. Combined with solid-phase extraction (SPE), the proposed method was effectively used for the determination of tetracycline residues in honey, achieving recovery rates ranging from 81.8% to 91.8%. The results suggest that this method is applicable for the detection of TC in complex food matrices.

Keywords

Tetracycline

Honey

Voltammetry

Glassy carbon electrode

Solid-phase extraction

Subjects