1
Advanced Micro and Nano Fabrication Devices Lab, Department of MEMS and NEMS, School of Intelligent Systems, College of Interdisciplinary Science and Technology, University of Tehran, Tehran, Iran
2
School of Energy Engineering and Sustainable Resources, College of Interdisciplinary Science and Technology, University of Tehran, Tehran, Iran
This article investigates an enzyme-based electrochemical biosensor for glucose detection using hydrothermal zinc oxide. To enhance sensitivity and accelerate electron transfer, multidimensional ZnO nanostructures were implemented within this electrochemical cell on a glass substrate. By employing zinc oxide nanostructures and various electrode configurations, sensitivity increased from 9.45 µAmM-1cm-2 to 21.12 µAmM-1cm-2. In this article, zinc oxide nanostructures were used in one-layered and multilayered manner, yielding sensitivities of 13.63 µAmM-1cm-2 and 21.12 µAmM-1cm-2, respectively. The sensor response is around 7.1 seconds and the device covers a valuable diagnostic range due to its low limit of detection and wide operational range (0.002–10 mM). Cyclic voltammetry (CV) and linear sweep voltammetry (LSV) were conducted for the biosensor both without and with the analyte. The maximum current peak observed at a scan rate of 200 mV/s at 60 mV was 70.06 µA for the sample coated with multilayered nanostructures of ZnO. These tests indicated that electron transfer via multilayer nanostructures was superior to that of single-layer nanostructures.
Sanjari,S , Koohsorkhi,J and Mehrpooya,M . (2025). Electrochemical Based Biosensor Using Multi-layer ZnO Nanostructures for Direct Detection of glucose. Analytical and Bioanalytical Electrochemistry, 17(1), 67-84. doi: 10.22034/abec.2025.720380
MLA
Sanjari,S , , Koohsorkhi,J , and Mehrpooya,M . "Electrochemical Based Biosensor Using Multi-layer ZnO Nanostructures for Direct Detection of glucose", Analytical and Bioanalytical Electrochemistry, 17, 1, 2025, 67-84. doi: 10.22034/abec.2025.720380
HARVARD
Sanjari S, Koohsorkhi J, Mehrpooya M. (2025). 'Electrochemical Based Biosensor Using Multi-layer ZnO Nanostructures for Direct Detection of glucose', Analytical and Bioanalytical Electrochemistry, 17(1), pp. 67-84. doi: 10.22034/abec.2025.720380
CHICAGO
S Sanjari, J Koohsorkhi and M Mehrpooya, "Electrochemical Based Biosensor Using Multi-layer ZnO Nanostructures for Direct Detection of glucose," Analytical and Bioanalytical Electrochemistry, 17 1 (2025): 67-84, doi: 10.22034/abec.2025.720380
VANCOUVER
Sanjari S, Koohsorkhi J, Mehrpooya M. Electrochemical Based Biosensor Using Multi-layer ZnO Nanostructures for Direct Detection of glucose. Anal. Bioanal. Electrochem.. 2025;17(1):67-84. doi: 10.22034/abec.2025.720380
