Document Type : Original Article
Authors
1
Department of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran
2
Department of Medical Techniques, Faculty of Health and Medical Technology, Middle Technical University, Baghdad, Iraq
3
Department of Radiological Techniques Department and Medical Technology, Middle Technical University, Baghdad, Iraq
4
Nanobiosensors Lab, Department of Life Science Engineering, Faculty of New Sciences & Technologies, University of Tehran, Tehran, Iran
5
Department of Biophysics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran
Abstract
Zinc oxide quantum dots (ZnO QDs) possess unique optical, electronic, and chemical properties due to the quantum confinement effect, making them ideal for sensing applications. Also, advances in sol-gel synthesis allow precise control over size, shape, and surface chemistry, improving functionality. By adjusting synthesis parameters, their effectiveness in optical and electrochemical applications has been increased. However, further research is needed to understand the relationship between synthesis parameters and performance fully. In this paper, ZnO QDs were synthesized using sol-gel techniques. The synthesis parameters, such as precursor concentrations, pH, temperature, and reaction time, were optimized to control the size, morphology, and properties of the ZnO QDs. The electrochemical characterization of the ZnO QDs was then studied by cyclic voltammetry utilizing K4[Fe(CN)6], as a known electrochemical probe in biosensing, in 0.1 M KCl solution. Also, a blood sample was used to find the electrochemical behavior of the ZnO QDs modified on a glassy carbon electrode (GCE) in a biological matrix. It was found that the modified working electrode, ZnO QDs/GCE, acts as an anti-oxidative in an alkaline blood medium and oxidative in the electrolyte of KCl.
Keywords
Subjects
