Analytical and Bioanalytical Electrochemistry

Analytical and Bioanalytical Electrochemistry

Quantum Dots in Breast Cancer: Emerging Nanobiotechnological Tools for Targeted Therapy and Diagnosis

Document Type : Review

Authors
1 Pharmaceutical Manufacturing, Department of Mechanical Engineering, Stevens Institute of Technology, Hoboken, NJ, USA
2 School of Pharmacy, RK University, Rajkot, Gujarat, India
Abstract
Breast cancer is the most common carcinoma in the recent era, and it is increasing day by day. There are various biomarkers for breast cancer, and the most important is human epidermal growth factor2 (HER2). Nanotechnology has advanced targeting systems for cancerous cells. Quantum dots (QDs) are nanoparticles which are used for bioimaging, biolabeling, and biosensing and synthesized by various techniques like top-down, bottom-up, and synthetic methods.  This review delves into various types of QDs like semiconductors, carbon QDs, graphene QDs, and many more. Each type of QDs has specific advantages regarding breast cancer treatment by delivering drugs into cancerous tissue, targeted delivery, and minimizing systemic toxicity. However, there are some challenges with respect to stability, pharmacokinetics, specificity with respect to breast cancer therapy. Future research is required to develop biocompatible QDs which hold the potential for the enhancement of therapeutic efficacy and the reduction of side effects.
Keywords

Subjects


Volume 17, Issue 7
July 2025
Pages 531-567

  • Receive Date 30 May 2025
  • Revise Date 08 July 2025
  • Accept Date 23 July 2025